A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

July 7, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Depression
Interventions
DRUG

Ketamine Hydrochloride

Intravenous 0.5 mg/kg infusions of ketamine for three consecutive days, 24 hours apart, with no more than 1mg/kg or 60 mg/day regardless of body weight

DRUG

Placebo

Intravenous 0.9% saline infusions for three consecutive days.

Trial Locations (1)

32224

RECRUITING

Mayo Clinic Florida, Jacksonville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER