Neoadjuvant Anti-PD-1 Immunotherapy With Chemotherapy in Resectable Locally Advanced Oral Squamous Cell Carcinoma

PHASE3RecruitingINTERVENTIONAL
Enrollment

309

Participants

Timeline

Start Date

November 21, 2023

Primary Completion Date

July 1, 2026

Study Completion Date

October 1, 2026

Conditions
Oral Squamous Cell Carcinoma
Interventions
DRUG

Camrelizumab plus TP

The participants will receive camrelizumab (200 mg) through intravenous infusion each 2-week cycle, and docetaxel (T) 75 mg/m2, cisplatin (P) 75 mg/m2 through intravenous infusion each 3-week cycle for 2 cycles.

DRUG

TP

The participants will receive docetaxel (T) 75 mg/m2, cisplatin (P) 75 mg/m2 through intravenous infusion each 3-week cycle for 2 cycles.

Trial Locations (3)

410008

RECRUITING

Xiangya Hospital of Central South University, Changsha

430079

RECRUITING

Hospital of Stomatology, Wuhan University, Wuhan

518036

NOT_YET_RECRUITING

Peking university Shenzhen hospital, Shenzhen

All Listed Sponsors
collaborator

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY

lead

Hospital of Stomatology, Wuhan University

OTHER