140
Participants
Start Date
June 1, 2023
Primary Completion Date
April 11, 2025
Study Completion Date
April 11, 2028
Weight loss intervention
Subjects will receive dietary counseling by a dietitian from 3 months post-partum of the 1st child until birth of the 2nd child. The mother (and father if overweight, BMI ≥25 kg/m\^2) will receive advice to provide a moderate caloric restriction (-500 to 1000 kcal/d) and power walk 2-4 times a week for a half an hour and attend physical activity sessions every 2nd week to attain a minimum weight loss of approximately 0,5-1,0 kg/week. The weight loss will last until a 10% weight loss (according to pre-pregnancy weight) has been achieved or until 1-year post-partum. If the subject has not achieved a weight loss of 10%, she or he will receive Very low-calorie diet (VLCD) until target weight loss is reached, though no longer than 8 weeks. After weight loss subjects will receive counseling to maintain weight loss and healthy weight gain during pregnancy until birth of the 2nd child.
RECRUITING
Aarhus University Hospital, Aarhus
Per Ovesen, Professor Dept. of Obsteterics, Aarhus University Hospital
UNKNOWN
Jens Meldgaard Bruun, Professor Steno Diabetes Center Aarhus, Aarhus University Hospital
UNKNOWN
Sine Knorr, PhD Steno Diabetes Center Aarhus, Aarhus University Hospital
UNKNOWN
Ulla Kampmann Opstrup
OTHER