PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus

NARecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

April 11, 2025

Study Completion Date

April 11, 2028

Conditions
Overweight and ObesityWeight LossPregnancy RelatedChild Nutrition SciencesBody Composition
Interventions
BEHAVIORAL

Weight loss intervention

Subjects will receive dietary counseling by a dietitian from 3 months post-partum of the 1st child until birth of the 2nd child. The mother (and father if overweight, BMI ≥25 kg/m\^2) will receive advice to provide a moderate caloric restriction (-500 to 1000 kcal/d) and power walk 2-4 times a week for a half an hour and attend physical activity sessions every 2nd week to attain a minimum weight loss of approximately 0,5-1,0 kg/week. The weight loss will last until a 10% weight loss (according to pre-pregnancy weight) has been achieved or until 1-year post-partum. If the subject has not achieved a weight loss of 10%, she or he will receive Very low-calorie diet (VLCD) until target weight loss is reached, though no longer than 8 weeks. After weight loss subjects will receive counseling to maintain weight loss and healthy weight gain during pregnancy until birth of the 2nd child.

Trial Locations (1)

8200

RECRUITING

Aarhus University Hospital, Aarhus

All Listed Sponsors
collaborator

Per Ovesen, Professor Dept. of Obsteterics, Aarhus University Hospital

UNKNOWN

collaborator

Jens Meldgaard Bruun, Professor Steno Diabetes Center Aarhus, Aarhus University Hospital

UNKNOWN

collaborator

Sine Knorr, PhD Steno Diabetes Center Aarhus, Aarhus University Hospital

UNKNOWN

lead

Ulla Kampmann Opstrup

OTHER