NCT05797168 - Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors | Biotech Hunter

Enrollment

506

Participants

Timeline

Start Date

June 5, 2023

Primary Completion Date

January 6, 2028

Study Completion Date

January 6, 2028

Conditions

Ovarian CancerLung AdenocarcinomaEndometrial Cancer

Interventions

DRUG

AZD5335

IV Antibody-drug conjugate

DRUG

Saruparib (AZD5305)

Oral PARP inhibitor

DRUG

Bevacizumab

IV Monoclonal antibody

DRUG

Carboplatin

IV Alkylating agent

DRUG

AZD9574

Oral PARP inhibitor

Trial Locations (60)

2170

RECRUITING

Research Site, Liverpool

3000

RECRUITING

Research Site, Melbourne

8035

RECRUITING

Research Site, Barcelona

10002

RECRUITING

Research Site, Taipei

11259

RECRUITING

Research Site, Taipei

13353

NOT_YET_RECRUITING

Research Site, Berlin

22031

RECRUITING

Research Site, Fairfax

28041

RECRUITING

Research Site, Madrid

28050

RECRUITING

Research Site, Madrid

29010

RECRUITING

Research Site, Málaga

30625

NOT_YET_RECRUITING

Research Site, Hanover

34718

RECRUITING

Research Site, Istanbul

40202

TERMINATED

Research Site, Louisville

40705

RECRUITING

Research Site, Taichung

43201

RECRUITING

Research Site, Columbus

45136

NOT_YET_RECRUITING

Research Site, Essen

48201

RECRUITING

Research Site, Detroit

52621

RECRUITING

Research Site, Ramat Gan

68167

NOT_YET_RECRUITING

Research Site, Mannheim

70403

RECRUITING

Research Site, Tainan City

77030

RECRUITING

Research Site, Houston

79106

NOT_YET_RECRUITING

Research Site, Freiburg im Breisgau

80045

RECRUITING

Research Site, Aurora

91010

RECRUITING

Research Site, Duarte

92093

WITHDRAWN

Research Site, La Jolla

92618

RECRUITING

Research Site, Irvine

93053

NOT_YET_RECRUITING

Research Site, Regensburg

97239

RECRUITING

Research Site, Portland

250117

RECRUITING

Research Site, Jinan

400030

RECRUITING

Research Site, Chongqing

450008

RECRUITING

Research Site, Zhengzhou

510000

RECRUITING

Research Site, Guangzhou

510060

RECRUITING

Research Site, Guangzhou

610041

RECRUITING

Research Site, Chengdu

710061

RECRUITING

Research Site, Xi'an

3109601

RECRUITING

Research Site, Haifa

02114

RECRUITING

Research Site, Boston

02903

RECRUITING

Research Site, Providence

02905

RECRUITING

Research Site, Providence

T6G 1Z2

RECRUITING

Research Site, Edmonton

N6A 5W9

RECRUITING

Research Site, London

M5G 2M9

RECRUITING

Research Site, Toronto

H2X 0A9

RECRUITING

Research Site, Montreal

H4A 3J1

RECRUITING

Research Site, Montreal

04103

NOT_YET_RECRUITING

Research Site, Leipzig

350-1298

RECRUITING

Research Site, Hidaka-shi

227-8577

RECRUITING

Research Site, Kashiwa

135-8550

RECRUITING

Research Site, Kōtoku

411-8777

RECRUITING

Research Site, Sunto-gun

104-0045

RECRUITING

Research Site, Tokyo

03080

NOT_YET_RECRUITING

Research Site, Seoul

06351

NOT_YET_RECRUITING

Research Site, Seoul

06050

RECRUITING

Research Site, Ankara

06200

RECRUITING

Research Site, Ankara

06800

RECRUITING

Research Site, Ankara

CB2 0XY

RECRUITING

Research Site, Cambridge

G12 0YN

RECRUITING

Research Site, Glasgow, Scotland

SE1 9RT

NOT_YET_RECRUITING

Research Site, London

SW3 6JJ

RECRUITING

Research Site, London

SM2 5PT

RECRUITING

Research Site, Sutton