Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity

RecruitingOBSERVATIONAL
Enrollment

2,000

Participants

Timeline

Start Date

July 23, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Irritable Bowel Syndrome (IBS)Sucrase Isomaltase Deficiency
Interventions
OTHER

Stool and saliva sample collection

Stool and saliva samples collection

OTHER

Questionnaire completion

"Questionnaire on;~* demographic, ethnicity, IBS subtype, post-infection onset, previous surgeries~* IBS severity score for adults~* Hospital Anxiety and Depression scores for adults~* Somatization score for adults~* Total glucose and fructose and excess fructose, lactose, sorbitol, mannitol, oligosaccharides (Fructans and GOS) as measured by CNAQ questionnaire for adults and children~* Quality of Life as measured by the PedsQL™ GI Symptoms Module~* GI symptoms as measured by the PedsQL™ GI Symptoms Module~* Anxiety, Depression as measured by the Pediatric PROMIS®"

Trial Locations (1)

NG7 2UH

RECRUITING

Nottingham University Hospitals NHS Trust, Nottingham

All Listed Sponsors
collaborator

CICbioGUNE

UNKNOWN

collaborator

Christian-Albrechts-University of Kiel

UNKNOWN

collaborator

University of Veterinary Medicine Hannover

UNKNOWN

lead

Nottingham University Hospitals NHS Trust

OTHER