Neoadjuvant Immunoradiotherapy With Evorpacept and Pembrolizumab in HPVOPC (Human Papilloma Virus Oropharynx Cancer)

PHASE2RecruitingINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

February 20, 2024

Primary Completion Date

August 20, 2026

Study Completion Date

May 30, 2028

Conditions
Oropharynx Cancer
Interventions
DRUG

Evorpacept

After stereotactic radiation to primary tumor and neck on week 1 of study, Evorpacept 45 mg/kg is administered by IV infusion every three weeks starting on Week 2, Day 1 of study for a total two 21-day cycles (6 weeks)

Trial Locations (3)

92093

RECRUITING

UC San Diego Moores Cancer Center, La Jolla

97213

RECRUITING

Providence Health & Services, Portland

97239

RECRUITING

Oregon Health and Science University, Portland

All Listed Sponsors
lead

University of California, San Diego

OTHER