A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

PHASE1TerminatedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

February 28, 2023

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
Relapsed or Refractory Acute Myeloid LeukemiaRelapsed or Refractory Chronic Myelomonocytic LeukemiaRelapsed or Refractory Myelodysplastic Syndrome
Interventions
DRUG

NC525

Monoclonal antibody specific for LAIR-1

Trial Locations (11)

10022

Weill Cornell Medicine, New York

14263

Roswell Park Cancer Institute, Buffalo

33136

University of Miami, Miami

44106

University Hospitals Cleveland Medical Center, Cleveland

44195

Cleveland Clinic, Cleveland

63110

Washington University School of Medicine in St. Louis, St Louis

77030

MD Anderson Cancer Center, Houston

91010

City of Hope, Duarte

97239

Oregon Health & Science University, Portland

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

NextCure, Inc.

INDUSTRY

NCT05787496 - A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms | Biotech Hunter | Biotech Hunter