The Efficacy and Safety of Rifaximin Treatment

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

March 9, 2023

Primary Completion Date

July 31, 2025

Study Completion Date

October 31, 2025

Conditions
Liver Failure, Acute on ChronicHepatic EncephalopathyHBVHepatitis BRifaximinEffect of Drug
Interventions
DRUG

Rifaximin 200 mg

Rifaximin Treatment Group:on the basis of comprehensive treatment of liver failure, Rifaximin will be added, three times a day, 400mg each time, for a total of 4 weeks, and we will observe until 12 weeks after withdrawal.

OTHER

Standard Treatment without Rifaximin

The standard treatment group (control group), which will receive routine comprehensive treatment for liver failure without Rifaximin.

Trial Locations (1)

510630

RECRUITING

The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER