140
Participants
Start Date
April 13, 2023
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2028
Microfracture
Use of standard tool kit to drill vertically from the periphery to the center with a hole spacing of 3\~4 mm with care to prevent penetrating adjacent holes. The hole depth should be 3\~5 mm and fat droplets or blood oozing is seen after loosening the tourniquet. However, no blood oozing is observed in some holes and in such case, the hole depth should be deepened to 5\~7 mm.
Chondro-Gide bilayer collagen membrane
After the Microfracture, the porous layer of the bilayer collagen membrane faces the bone surface. The already trimmed, cut and wetted membrane is insert into the defect and fixed symmetrically with absorbable surgical suture with needle. Knots are put on the pinhole of collagen membrane to avoid tearing of surrounding cartilage or collagen membrane during knotting.
Sino-Japanese Friendship Hospital, Beijing
Peking University Third Hospital, Beijing
The Second Hospital of Jilin University, Changchun
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing
QiLu Hospital of Shan Dong University, Jinan
The second affiliated hospital of Zhejiang University School of Medicine, Hanzhou
Tai Zhou Hospital of Zhe Jiang Province, Taizhou
Nan Chang First Hospital, Nanchang
The First Affiliated Hospital Of Nanchang University, Nanchang
The First Affiliated Hospital of Jinan University, Guangzhou
The Third Affiliated Hospital of Southern Medical University, Guangzhou
Shen Zhen Secondary People hospital, Shenzhen
Peking University Shen Zhen hospital, Shenzhen
The Second People Hospital of Yi Bin, Yibin
The First Affiliated Hospital of Kunming Medical University, Kunming
The First People Hospital of Ka Shi, Kashgar
The Second Hospital of Tang Shan, Tangshan
Inner Mongolia People's Hospital, Hohhot
Lead Sponsor
TigerMed
INDUSTRY
Geistlich Pharma AG
INDUSTRY