500
Participants
Start Date
August 23, 2019
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2033
Blood Collection, processing and analyses
20ml of blood will be drawn from study participant at the baseline visit for molecular analyses.
Gastroscopy and biopsies collection
Study participant will undergo gastroscopy with collection of gastric mucosal biopsies at the baseline visit to ascertain OLGIM status and for molecular analyses. Study participant will undergo surveillance gastroscopy for gastric cancer at years 2 and 4 to assess whether they have reached endpoint.
Urea Breath Test
Study participant will fast for 6 hours or overnight before undergoing the Urea Breath Test (UBT) to test for current H. pylori infection. Breath collection will be performed before ingestion of 13C urea, and at specified time intervals after ingestion.
Stanford University, Stanford
National University Hospital, Singapore
Singapore General Hospital, Singapore
Tan Tock Seng Hospital, Singapore, Singapore
The Chinese University of Hong Kong, Hong Kong
Nihon University School of Medicine, Tokyo
Yonsei University, Republic of Korea, Seoul
National Taiwan University Hospital, Taipei
Tan Tock Seng Hospital
OTHER
Singapore General Hospital
OTHER
Yonsei University
OTHER
Stanford University
OTHER
Chinese University of Hong Kong
OTHER
Nihon University
OTHER
National Taiwan University Hospital
OTHER
National University Hospital, Singapore
OTHER