Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

February 28, 2026

Conditions
Bronchopulmonary Dysplasia
Interventions
PROCEDURE

Gastric Feeds

The participant will receive nutrition via a nasogastric tube. Gastric feedings will be administered as bolus feeds every 3 hours over 1 hour. Infants who are deemed able to advance oral feedings via mouth during the study period will be permitted to do so, and this will be recorded.

PROCEDURE

Jejunal Feeds

The participant will receive nutrition via a nasojejunal tube. Postpyloric feedings will be administered continuously into the jejunum. Infants who are deemed able to advance oral feedings via mouth during the study period will be permitted to do so, and this will be recorded.

Trial Locations (1)

02115

RECRUITING

Boston Children's Hospital, Boston

All Listed Sponsors
collaborator

Beth Israel Deaconess Medical Center

OTHER

lead

Boston Children's Hospital

OTHER