149
Participants
Start Date
March 20, 2023
Primary Completion Date
April 15, 2024
Study Completion Date
April 15, 2024
MB-102
18.6 mg/mL in a 7.0 mL volume administered by intravenous injection over 30 - 60 seconds, followed by a 10 mL normal saline flush administered intravenously over 30 - 60 seconds
MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
On treatment day, participants had the TGFR reusable sensor with disposable adhesive ring placed on their chest, and the MediBeacon® Transdermal GFR Measurement System was initiated to collect background fluorescence. When this was completed, participants received a single dose of MB-102. Fluorescent measurements were collected for 12-24 hours. For those with significant renal compromise, fluorescent measurements were continued until the sensor no longer detected MB-102 in the body.
Centricity Research, Columbus
Research by Design, LLC, Chicago
Clinical Advancement Center, PLLC, San Antonio
Endeavor Clinical Trials, LLC, San Antonio
PPD, Austin
Lead Sponsor
MediBeacon
INDUSTRY