Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)

PHASE2CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

March 27, 2023

Primary Completion Date

January 29, 2025

Study Completion Date

January 29, 2025

Conditions
Spinal Cord InjuriesTetraplegiaParaplegiaMuscle LossAtrophy, MuscularInsulin Resistance
Interventions
DRUG

Ursolic Acid

Subjects will take an oral 400mg (8 capsules - 4 in the morning/200mg and 4 at night/200mg) supplement of UA every day for 12 weeks.

OTHER

Strength Training

Subjects will perform 3 sets of 10 repetitions of concentric and eccentric upper body exercises (bicep curls and tricep extensions) each session. Each session will last approximately 10-15 minutes of weightlifting with a 2-minute rest period between sets. The arm selected for exercise will be randomized.

Trial Locations (1)

33136

University of Miami - Miami Project to Cure Paralysis, Miami

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Florida

OTHER

lead

University of Miami

OTHER

NCT05776862 - Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI) | Biotech Hunter | Biotech Hunter