Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)

NARecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

July 19, 2024

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2027

Conditions
Diabetes Mellitus, Type 2
Interventions
BEHAVIORAL

Nutrition visits

Participants will receive exercise and dietary counseling from a nutritionist and registered dietician with extensive experience with diabetes and obesity every 2 weeks during the 12 wee

OTHER

Intensification of diabetes regimen

Patient will meet every 2 weeks in person or have regular phone calls with an endocrinologist to review glucose control and intensification of the diabetes regimens. Will follow the general strategies outlined in the Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes.

OTHER

Continuous glucose monitor (CGM)

Individuals with uncontrolled T2DM will be asked use a CGM during the 12 week intervention, to monitor glucose control. Target blood glucose levels will be between 80-130 mg/dl before meals and \< 180 mg/dl at bedtime. Individuals not at goal with glycemic targets will undergo intensification of their regimen. Throughout the study, individuals will be contacted via telephone, email or through additional clinic visits as deemed necessary for maintenance of glycemic control.

Trial Locations (1)

06520

RECRUITING

Yale New Haven Hospital (YNHH) Research Unit (HRU), New Haven

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Yale University

OTHER