Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring

NARecruitingINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

May 31, 2026

Study Completion Date

December 1, 2026

Conditions
Cervical CancerCervical DysplasiaOropharyngeal CancerHuman Papillomavirus Infection
Interventions
DIAGNOSTIC_TEST

Arm A - Diagnostic test: HPV detection in liquid biopsies

Patients will be asked to perform self-collection of gargle lavage samples. Oropharyngeal swabs, breath condensate, and blood samples will be taken by trained clinicians.

DIAGNOSTIC_TEST

Arm B - Diagnostic test: HPV detection in liquid biopsies

Patients will be asked to perform cervicovaginal self-sampling using Evalyn Brush. Blood samples will be taken by trained clinicians.

Trial Locations (1)

77900

RECRUITING

University Hospital Olomouc, Olomouc

All Listed Sponsors
collaborator

National Institute for Cancer Research, Czech Republic

OTHER

collaborator

University Hospital Olomouc

OTHER

lead

The Institute of Molecular and Translational Medicine, Czech Republic

OTHER