A Study Explore WJB001 Capsules in Patients With Advanced Solid Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

May 5, 2023

Primary Completion Date

April 8, 2026

Study Completion Date

May 23, 2026

Conditions
Advanced Solid Tumors
Interventions
DRUG

WJB001

"Dose Escalation:~Accelerated titration (the first two dose groups) and BOIN combination (the subsequent dose group) were used for dose escalation.~Dose Expansion:~Based on the previous data, 1 to 2 doses were selected to further evaluate the initial efficacy, safety, tolerability and pharmacokinetic characteristics to confirm RP2D.~Cohort Expansion:~The preliminary plan of cohort expansion phase uses the Simon two-stage optimal method to expand 2 to 3 cohorts."

Trial Locations (10)

100021

RECRUITING

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

110000

RECRUITING

Liaoning Cancer Hospital, Shenyang

350000

RECRUITING

Fujian Cancer Hospital, Fuzhou

410000

RECRUITING

Hunan Cancer Hospital, Changsha

430023

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

450000

RECRUITING

Henan Cancer Hospital, Henan

510000

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

530000

RECRUITING

Tumor Hospital Affiliated to Guangxi Medical University, Nanning

710061

RECRUITING

The First Affiliated Hospital of Xi 'an Jiaotong University, Xi’an

030000

RECRUITING

Shanxi Cancer Hospital, Taiyuan

All Listed Sponsors
collaborator

Sponsor GmbH

OTHER

lead

Wigen Biomedicine Technology (Shanghai) Co., Ltd.

INDUSTRY