Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations

PHASE4RecruitingINTERVENTIONAL
Enrollment

1,311

Participants

Timeline

Start Date

March 5, 2024

Primary Completion Date

June 30, 2028

Study Completion Date

November 30, 2028

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Azithromycin Pill

"Participants will take azithromycin according to their standard of care prescription.~If the participant is on the seasonal azithromycin treatment arm, they will only take azithromycin during the winter months (October-March) followed by matched placebo (April-September)."

DRUG

Placebo

The placebo tablets will be matched in appearance, taste and smell to the azithromycin tablets.

Trial Locations (1)

CB2 0QQ

RECRUITING

Cambridge University Hospital NHS Trust, Addenbrookes Hospital, Cambridge

All Listed Sponsors
collaborator

University of Aberdeen

OTHER

collaborator

NHS Greater Glasgow and Clyde

OTHER

collaborator

University of East Anglia

OTHER

collaborator

Nottingham City Hospital

UNKNOWN

collaborator

Swansea University

OTHER

collaborator

Newcastle University

OTHER

collaborator

University of Cambridge

OTHER

collaborator

NHS Sunderland Clinical Commissioning Group

UNKNOWN

collaborator

Liverpool School of Tropical Medicine

OTHER

collaborator

Royal Brompton & Harefield NHS Foundation Trust

OTHER

collaborator

University College London Hospitals

OTHER

collaborator

Liverpool Heart and Chest Hospital NHS Foundation Trust

OTHER

collaborator

Imperial College London

OTHER

collaborator

Red Graphic

UNKNOWN

collaborator

Eramol (UK) Ltd.

UNKNOWN

collaborator

WGK Clinical Services Ltd.

UNKNOWN

collaborator

Sealed Envelope Ltd.

UNKNOWN

collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

lead

Dr Ian B Wilkinson

OTHER