(Neo)Adjuvant BRAF/MEK Inhibition in pN1c Melanoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

January 1, 2022

Primary Completion Date

January 1, 2026

Study Completion Date

January 1, 2026

Conditions
Melanoma Stage IIIIn-Transit Metastasis of Cutaneous Melanoma
Interventions
DRUG

Encorafenib + Binimetinib

"In the open label phase II study, the combination of BRAF/MEK inhibition with encorafenib/binimetinib in the neo-adjuvant setting will be investigated.~Furthermore, efficacy of adjuvant BRAF/MEK inhibition with encorafenib/binimetinib, for 44 weeks will be evaluated."

Trial Locations (1)

2311GP

RECRUITING

Leiden University Medical Center, Leiden

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pierre Fabre Laboratories

INDUSTRY

lead

Leiden University Medical Center

OTHER