Neoantigen Derived DCs as Cancer Treatment

PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

March 30, 2025

Study Completion Date

March 30, 2026

Conditions
Refractory TumorSolid Tumor
Interventions
BIOLOGICAL

Dendritic Cell Vaccine

Approximately 1.5 x 10\^6±20% cells will be subcutaneously injected to the patient's inguinal area (either left side or right side can be injected, only one area will be injected each time) on day 1, 8, 15, 29, 85, 141, 197, 253 and 309.

DRUG

Lenvatinib

Lenvatinib 10mg/day on day 43-77

DRUG

Nivolumab

Nivolumab 3mg/kg on day 43, 57 and 71.

Trial Locations (3)

Unknown

NOT_YET_RECRUITING

Kaohsiung Medical University Hospital, Kaohsiung City

RECRUITING

National Cheng-Kung University Hospital, Tainan City

RECRUITING

National Institute of Cancer Research, Tainan City

All Listed Sponsors
collaborator

National Cheng-Kung University Hospital

OTHER

lead

National Health Research Institutes, Taiwan

OTHER