450
Participants
Start Date
June 12, 2023
Primary Completion Date
January 9, 2026
Study Completion Date
January 9, 2026
Dapagliflozin propanediol (FORXIGA™/FARXIGA™1)
"Dapagliflozin (10 mg per day; per os) on top of standard of care as recommended in current guidelines\* for 6 months (experimental group)~\*All patients will receive optimal medical therapy (including antithrombotic, beta-blockers, statins, angiotensin converting enzyme inhibitors or angiotensin receptor blocker or sacubitril/valsartan, diuretics, antagonists of the mineralocorticoid receptor) according to their clinical condition as recommended."
Placebo comparator
"Placebo daily on top of standard of care as recommended in current guidelines\* for 6 months (control group)~\*All patients will receive optimal medical therapy (including antithrombotic, beta-blockers, statins, angiotensin converting enzyme inhibitors or angiotensin receptor blocker or sacubitril/valsartan, diuretics, antagonists of the mineralocorticoid receptor) according to their clinical condition as recommended."
RECRUITING
Department of Cardiology AP-HP Hôpital européen Georges - Pompidou, Paris
Collaborators (1)
AstraZeneca
INDUSTRY
Assistance Publique - Hôpitaux de Paris
OTHER