The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

December 11, 2023

Primary Completion Date

June 1, 2027

Study Completion Date

June 30, 2027

Conditions
Paroxysmal Supraventricular Tachycardia
Interventions
DRUG

Etripamil NS

"Part 1A: At least 12 patients will be administered with Etripamil NS (35 mg/100 μL per nostril) at a dose of 70 mg.~Part 1B: At least 18 following patients will be administered with Etripamil NS at a dose determined by analysis of data generated from Part 1A.~Part 2A: At least 12 patients will be administered with Etripamil NS at a dose selected based on appropriate body size-based modeling using PK assessments, as well as safety/tolerability, and efficacy data collected in Part 1.~Part 2B: At least 18 following patients will be administered with Etripamil NS at a dose determined by analysis of data generated from Part 2A."

Trial Locations (10)

28046

RECRUITING

Hospital Infantil Universitario La Paz, Madrid

37075

NOT_YET_RECRUITING

Universitätsmedizin Göttingen, Klinik für Pädiatrische Kardiologie, Intensivmedizin und Neonatologie, Göttingen

38103

NOT_YET_RECRUITING

Le Bonheur Children's Hospital, Memphis

45229

NOT_YET_RECRUITING

Cincinnati Children's Hospital Medical Center, Cincinnati

60453

NOT_YET_RECRUITING

Advocate Children's Hospital, Oak Lawn

77030

NOT_YET_RECRUITING

Baylor College of Medicine, Houston

85016

RECRUITING

Phoenix Children's Hospital, Phoenix

97239

RECRUITING

Oregon Health and Science University, Portland

V6H3V4

NOT_YET_RECRUITING

The University of British Columbia, Vancouver

08950

NOT_YET_RECRUITING

Hospital Sant Joan de Déu, Barcelona

Sponsors
All Listed Sponsors
lead

Milestone Pharmaceuticals Inc.

OTHER

NCT05763953 - The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients) | Biotech Hunter | Biotech Hunter