NCT05761860View on ClinicalTrials.gov

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

September 12, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

December 31, 2026

Conditions
Pain
Interventions
DRUG

OxyCODONE 5 mg Oral Tablet

Oxycodone 5mg oral administration

DRUG

OxyCODONE 2.5 mg Oral Tablet

Oxycodone 2.5mg oral administration

OTHER

Placebo oxyCODONE Oral Tablet

Oxycodone 0mg (placebo) oral administration

DRUG

Oxytocin Nasal Spray (48 IU)

Intranasal oxytocin administration (48 IU)

OTHER

Placebo Oxytocin Nasal Spray

Intranasal oxytocin placebo administration

Trial Locations (1)

32611

RECRUITING

University of Florida, Gainesville

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

University of Florida

OTHER