151
Participants
Start Date
December 13, 2023
Primary Completion Date
June 30, 2026
Study Completion Date
October 31, 2026
Phase Ia dose-escalation part of FB849 Monotherapy
At a given level dose once daily
Phase Ib dose-expansion of FB849 monotherapy
At recommended dose for expansion cohort once daily
Phase IIb dose-escalation part of FB849 in Combination with Pembrolizumab
At recommended dose for expansion cohort once daily in combination with pembrolizumab
Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type A cancer)
At recommended dose for expansion cohort once daily in combination with pembrolizumab
Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type B cancer)
At recommended dose for expansion cohort once daily in combination with pembrolizumab
Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type C cancer)
At recommended dose for expansion cohort once daily in combination with pembrolizumab
RECRUITING
Next Oncology Virginia, Fairfax
RECRUITING
Mary Crowley Cancer Research Center, Dallas
RECRUITING
Cleveland Clinic, Cleveland
RECRUITING
NEXT Oncology San Antonio, San Antonio
RECRUITING
Summit Cancer Centers - Spokane Valley, Spokane
Lead Sponsor
Merck Sharp & Dohme LLC
INDUSTRY
1ST Biotherapeutics, Inc.
INDUSTRY