140
Participants
Start Date
April 13, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
July 1, 2026
Investigational Product - MIB 626
The eligible participants will be assigned to receive either NMN or placebo using concealed block randomization in a 1:1 ratio, stratified by sex (male, female), age (60 to 75, \>75 years) and trial site. The randomization list will be generated by the unblinded biostatistician using the software R (www.r-project.org), and deployed in a secure, centralized web-based application accessible to study staff following confirmation of a participant's eligibility.
Placebo
Placebo - Participants randomized to placebo will receive Matching placebo tablets will be provided by Metro International Biotech, LLC.
RECRUITING
Brigham and Women's Hospital, Boston
Collaborators (1)
Boston Medical Center
OTHER
Brigham and Women's Hospital
OTHER