NAD Augmentation in Diabetes Kidney Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 13, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

July 1, 2026

Conditions
Type2diabetesDiabetic Kidney Disease
Interventions
DRUG

Investigational Product - MIB 626

The eligible participants will be assigned to receive either NMN or placebo using concealed block randomization in a 1:1 ratio, stratified by sex (male, female), age (60 to 75, \>75 years) and trial site. The randomization list will be generated by the unblinded biostatistician using the software R (www.r-project.org), and deployed in a secure, centralized web-based application accessible to study staff following confirmation of a participant's eligibility.

DRUG

Placebo

Placebo - Participants randomized to placebo will receive Matching placebo tablets will be provided by Metro International Biotech, LLC.

Trial Locations (1)

02115

RECRUITING

Brigham and Women's Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Boston Medical Center

OTHER

lead

Brigham and Women's Hospital

OTHER