200
Participants
Start Date
April 17, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
September 30, 2026
Selective Cytopheretic Device
"The Selective Cytopheretic Device (SCD) is comprised of tubing, connectors, and a synthetic hollow fiber membrane cartridge. The device is connected in series to a commercially available CKRT hemofilter. Blood from the CKRT circuit is diverted after the CKRT hemofilter through to the extracapillary space (ECS) of the SCD cartridge. Blood circulates through the SCD ECS and then it is returned to the patient via the venous return line of the CKRT circuit. Regional citrate anticoagulation is used for the entire CKRT and SCD blood circuit.~The SCD cartridge incorporates a synthetic hollow fiber membrane with the ability to bind activated leukocytes to its extracapillary surface; and when used in a CKRT extracorporeal circuit in the presence of regional citrate anticoagulation, the SCD modulates inflammation."
Standard of Care
Standard of care CKRT for the subject's condition, as appropriate
WITHDRAWN
Unversity of Rochester, Rochester
NOT_YET_RECRUITING
St Luke's University Hospital, Bethlehem
RECRUITING
Saint Mary Medical Center, Langhorne
NOT_YET_RECRUITING
Nazareth Hospital, Philadelphia
NOT_YET_RECRUITING
Virginia Commonwealth University, Richmond
RECRUITING
Sentara Health, Norfolk
WITHDRAWN
JMS Burn Center, Augusta
NOT_YET_RECRUITING
Orlando Regional Medical Center, Orlando
NOT_YET_RECRUITING
University of Alabama Birmingham Hospital, Birmingham
WITHDRAWN
University of Kentucky HealthCare, Lexington
RECRUITING
Cleveland Clinic, Cleveland
RECRUITING
University of Cincinnati, Cincinnati
RECRUITING
University of Michigan, Ann Arbor
RECRUITING
Henry Ford Medical Center, Detroit
RECRUITING
University of Iowa Hospital, Iowa City
RECRUITING
Mayo Clinic, Rochester
RECRUITING
Ochsner LSU Health Academic Medical Center, Shreveport
WITHDRAWN
Central Arkansas Veterans Healthcare, Little Rock
RECRUITING
University of Texas Southwestern Medical Center, Dallas
RECRUITING
Methodist Hospital Metropolitan, San Antonio
RECRUITING
Methodist Hospital, San Antonio
RECRUITING
University of Texas Health San Antonio, San Antonio
RECRUITING
Brooke Army Medical Center, Fort Sam Houston
RECRUITING
United States Army Institute of Surgical Research, JBSA Fort Sam Houston
WITHDRAWN
University of Colorado Hospital Anschutz Medical Campus, Aurora
NOT_YET_RECRUITING
UNLV Health, Las Vegas
NOT_YET_RECRUITING
Ronald Reagan UCLA Medical Center, Los Angeles
RECRUITING
Stanford University, Palo Alto
RECRUITING
Samaritan Health, Corvallis
Lead Sponsor
SeaStar Medical
INDUSTRY