Efficacy and Safety of Super-hyperfractionation Pulse Radiotherapy Combined With ICIs for Advanced NSCLC

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

March 1, 2026

Study Completion Date

March 1, 2026

Conditions
Lung CancerImmune Checkpoint InhibitorRadiotherapy
Interventions
RADIATION

Super-hyperfractionation Pulse Radiotherapy

Radiotherapy design: a single dose of 0.5Gy, 16 consecutive pulses with an interval of 3 minutes (0.5Gy \* 16F), total dose DT: 8Gy; Immunotherapy: PD-1/PD-L1 monoclonal antibodies conforming to CSCO guidelines for lung cancer indications, including Carrilizumab, Tirelizumab, Teripril, Paborizumab, etc., conventional therapeutic dose, Q3W, until progression or the investigator judges that there is no longer clinical benefit or intolerable side effects.

Trial Locations (2)

40037

RECRUITING

the second affiliated hospital of Army medical university, Chongqing

400000

NOT_YET_RECRUITING

Jianguo Sun, Chongqing

All Listed Sponsors
lead

Xinqiao Hospital of Chongqing

OTHER