Prognostic Study of HPV Virus Integration in Women With HSIL

RecruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

September 30, 2025

Study Completion Date

October 31, 2025

Conditions
HPV InfectionVirus IntegrationHSIL, High Grade Squamous Intraepithelial Lesions
Interventions
OTHER

Follow up

Four samples of cervical exfoliated cells and fornix secretions were collected from all subjects at enrollment, 6 months, 12 months and 24 months for HPV integration status and vaginal microbiota diversity sequencing, and two additional samples of peripheral blood (whole blood + serum) were collected at enrollment.

Trial Locations (13)

350001

RECRUITING

Fujian Maternity and Child Health Hospital, Fuzhou

Unknown

ACTIVE_NOT_RECRUITING

Longyan First Hospital, Longyan

ACTIVE_NOT_RECRUITING

Longyan People's Hospital, Longyan

RECRUITING

Nanping Second Hospital, Nanping

RECRUITING

Mindong Hospital of Ningde City, Ningde

ACTIVE_NOT_RECRUITING

Ningde City Hospital, Ningde

ACTIVE_NOT_RECRUITING

Affiliated Hospital of Putian University, Putian

RECRUITING

Putian First Hospital, Putian

RECRUITING

Sanming Second Hospital, Sanming

RECRUITING

Shenzhen Maternity and child Healthcare Hospital, Shenzhen

ACTIVE_NOT_RECRUITING

Shijiazhuang Obstetrics and Gynecology Hospital, Shijiazhuang

ACTIVE_NOT_RECRUITING

Affiliated Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

ACTIVE_NOT_RECRUITING

Maternal and Child Health Hospital of Hubei Province, Wuhan

All Listed Sponsors
lead

Fujian Maternity and Child Health Hospital

OTHER