Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation

PHASE4RecruitingINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

September 25, 2023

Primary Completion Date

April 25, 2025

Study Completion Date

April 25, 2025

Conditions
Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy
Interventions
DRUG

Thymoglobulin 25 milligrams (mg) Injection

Patients will receive thymoglobulin between 5 and 20 milligrams/kilograms (mg/kg) as an intravenous infusion over a period of 2 to 5 days depending on the dose and the transplant package chosen by the physician.

BIOLOGICAL

blood test

"Thymoglobulin® serum levels~Time frame : samples will be drawn at the following points :~* 1 after each end of perfusion ;~* 1 though concentration before each perfusion ;~* 3 blood samples in 3 different days during the first week;~* 1 weekly for 2 weeks post HSCT."

Trial Locations (2)

69008

RECRUITING

Institut d'Hématologie et d'Oncologie Pédiatrique, Lyon

69495

RECRUITING

Centre Hospitalier Lyon Sud, Pierre-Bénite

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER