Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

369

Participants

Timeline

Start Date

June 29, 2023

Primary Completion Date

October 31, 2026

Study Completion Date

January 30, 2027

Conditions
Arterial StiffnessWhite Matter LesionsCognitive Decline
Interventions
DRUG

S-equol

Experimental drug

DRUG

Placebo

Placebo - 10 mg per day for 24 months of tablets that will be the same size/shape/color as the s-equol tablets.

Trial Locations (3)

15213

University of Pittsburgh, Pittsburgh

27157

Wake Forest University Health Sciences, Winston-Salem

30322

Emory University, Atlanta

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

Akira Sekikawa

OTHER