Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidism

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

March 31, 2024

Study Completion Date

June 30, 2024

Conditions
HypothyroidismPrimary HypothyroidismVitamin C Deficiency
Interventions
DRUG

Vitamin C

The patient in test group will be provided vitamin C effervescent tablets to use 1 gram daily with their usual dose of Levothyroxine for 12 weeks, with thyroid function tests assessed at 6 and 12 weeks. The patients who wish to continue at the end of 12 weeks will be provided another 12 weeks supply of vitamin C effervescent tablets to use 1 gram daily with their usual dose of Levothyroxine for with thyroid function tests and clinical score assessed at the end of week 24.

DRUG

Oral Rehydration Salt Formulations

The patients in control group will have a oral rehydration effervescent tablet to take with their usual dose of Levothyroxine for 12 weeks, with thyroid function tests assessed at 6 and 12 weeks. The control group will then be provided vitamin C (intervention) effervescent tablets to use 1 gram daily with their usual dose of Levothyroxine for 12 weeks, with thyroid function tests assessed at 6 and 12 weeks to see if there is any difference on biochemical testing or clinical scores.

Trial Locations (1)

15551

RECRUITING

Internal Medicine, College of Medicine and Health Sciences, Al Ain City

All Listed Sponsors
lead

Dr Adnan Agha

OTHER