Steroids in Occipital Nerve Block for Treatment of Headache

PHASE4CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

February 17, 2023

Primary Completion Date

June 1, 2025

Study Completion Date

June 1, 2025

Conditions
HeadacheOccipital Nerve Block
Interventions
DRUG

Bupivacaine

2 mL of bupivacaine 0.5% (5 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves

DRUG

Lidocaine

0.5 mL of lidocaine 1% (10 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves

DRUG

Dexamethasone

0.5 mL of dexamethasone (10 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves

DRUG

Normal saline

0.5 mL of normal saline 0.9% injected at the origin of each bilateral greater and lesser occipital nerves

PROCEDURE

Greater/lesser occipital nerve blocks

Subjects will receive a total of 12 mL injectate divided equally between the 4 injection sites of the bilateral greater and lesser occipital nerves using the landmark-based technique.

Trial Locations (1)

55905

Mayo Clinic Minnesota, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT05732532 - Steroids in Occipital Nerve Block for Treatment of Headache | Biotech Hunter | Biotech Hunter