Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

April 4, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

August 31, 2027

Conditions
Colorectal CancerSolid Tumors
Interventions
DRUG

Revumenib

Revumenib administered orally with or without food. Participants may continue to receive treatment until disease progression or until they experience unacceptable toxicity.

DRUG

Chemotherapy

Either Lonsurf® or Stivarga® administered per the investigator's choice at the respective drug label's dose and schedule. Participants may continue to receive treatment until disease progression or until they experience unacceptable toxicity.

Trial Locations (6)

10065

Memorial Sloan Kettering Cancer Center, Manhattan

22031

Inova Schar Cancer Institute, Fairfax

37232

Vanderbilt-Ingram Cancer Center, Nashville

44718

Gabrail Cancer Center, Canton

85258

Honor Health Research Institute, Scottsdale

02114

Massachusetts General Hospital, Boston

Sponsors
All Listed Sponsors
lead

Syndax Pharmaceuticals

INDUSTRY