A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

PHASE2RecruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

January 12, 2023

Primary Completion Date

June 17, 2026

Study Completion Date

March 24, 2027

Conditions
Colitis Ulcerative
Interventions
DRUG

Dupilumab

injection solution subcutaneous

DRUG

Placebo

injection solution subcutaneous

Trial Locations (77)

404

COMPLETED

Investigational Site Number : 1580002, Taichung

1028

RECRUITING

Investigational Site Number : 0320007, Buenos Aires

1119

RECRUITING

Investigational Site Number : 0320008, Buenos Aires

1125

RECRUITING

Investigational Site Number : 0320002, Buenos Aires

1619

RECRUITING

Investigational Site Number : 7100008, Johannesburg

1821

RECRUITING

Investigational Site Number : 7100006, Johannesburg

2017

RECRUITING

Investigational Site Number : 7100001, Johannesburg

4000

RECRUITING

Investigational Site Number : 0320001, San Miguel de Tucumán

RECRUITING

Investigational Site Number : 0320004, San Miguel de Tucumán

6045

RECRUITING

Investigational Site Number : 7100003, Port Elizabeth

7405

RECRUITING

Investigational Site Number : 7100005, Cape Town

7500

RECRUITING

Investigational Site Number : 7100009, Cape Town

7600

RECRUITING

Investigational Site Number : 0320006, Mar del Plata

7708

RECRUITING

Investigational Site Number : 7100002, Cape Town

7800

RECRUITING

Investigational Site Number : 7100007, Cape Town

11372

RECRUITING

Smart Medical Research Inc- Site Number : 8400037, Jackson Heights

11758

RECRUITING

DiGiovanna Family Care- Site Number : 8400006, Massapequa

15213

RECRUITING

UPMC Presbyterian- Site Number : 8400038, Pittsburgh

25020

RECRUITING

Investigational Site Number : 4840005, Saltillo

26426

RECRUITING

Investigational Site Number : 4100002, Wŏnju

27000

RECRUITING

Investigational Site Number : 4840002, Torreón

27310

RECRUITING

Investigational Site Number : 7920003, Gaziantep

28287

RECRUITING

Tryon Medical Partners - Charlotte - Piedmont Row Drive South- Site Number : 8400008, Charlotte

28358

COMPLETED

Care Access - Lumberton- Site Number : 8400018, Lumberton

30076

RECRUITING

Gastroenterology Consultants - Roswell- Site Number : 8400022, Roswell

31000

RECRUITING

Investigational Site Number : 4840003, Chihuahua City

32073

RECRUITING

Digestive Disease Consultants - Orange Park- Site Number : 8400042, Orange Park

33016

RECRUITING

Wellness Clinical Research - Miami Lakes - 8181 Northwest 154th Street- Site Number : 8400009, Miami Lakes

33025

RECRUITING

Tellabio International Research Services- Site Number : 8400041, Pembroke Pines

33033

RECRUITING

Homestead Associates in Research- Site Number : 8400004, Homestead

33070

RECRUITING

Investigational Site Number : 7920001, Mersin

33609

RECRUITING

GCP Clinical Research- Site Number : 8400014, Tampa

34102

RECRUITING

GI PROS Research- Site Number : 8400046, Naples

34653

RECRUITING

Advanced Research Institute - New Port Richey- Site Number : 8400026, New Port Richey

34734

RECRUITING

Investigational Site Number : 7920005, Istanbul

34943

RECRUITING

Investigational Site Number : 4100006, Daejeon

41944

RECRUITING

Investigational Site Number : 4100005, Daegu

42415

RECRUITING

Investigational Site Number : 4100004, Daegu

44100

RECRUITING

Investigational Site Number : 4840007, Guadalajara

48108

RECRUITING

Investigational Site Number : 4100003, Haeundae-gu

67000

RECRUITING

Investigational Site Number : 7920006, Zonguldak

75092

RECRUITING

Medrasa Clinical Research - Medrasa Sherman- Site Number : 8400039, Sherman

75701

RECRUITING

Digestive Health Specialists of Tyler- Site Number : 8400031, Tyler

76092

RECRUITING

Texas Digestive Disease Consultants - Southlake- Site Number : 8400013, Southlake

76234

RECRUITING

Advanced Gastroenterology Associates, PA- Site Number : 8400047, Decatur

77494

RECRUITING

Katy Integrative Gastroenterology- Site Number : 8400027, Katy

77904

RECRUITING

Victoria Gastroenterology- Site Number : 8400019, Victoria

90211

RECRUITING

TLC Clinical Research- Site Number : 8400020, Beverly Hills

91360

RECRUITING

Clinical Trials Management Services - Thousand Oaks- Site Number : 8400034, Thousand Oaks

92262

RECRUITING

Palmtree Clinical Research- Site Number : 8400048, Palm Springs

92307

RECRUITING

Om Research- Site Number : 8400029, Apple Valley

93012

RECRUITING

Ventura County Gastroenterology Medical Group- Site Number : 8400028, Camarillo

98004

RECRUITING

Washington Gastroenterology - Bellevue- Site Number : 8400025, Bellevue

98405

RECRUITING

Washington Gastroenterology - Tacoma- Site Number : 8400030, Tacoma

4070038

RECRUITING

Investigational Site Number : 1520001, Concepción

7620001

RECRUITING

Investigational Site Number : 1520005, Santiago

8330034

RECRUITING

Investigational Site Number : 1520003, Santiago

8360160

RECRUITING

Investigational Site Number : 1520006, Santiago

8380456

RECRUITING

Investigational Site Number : 1520002, Santiago

07018

RECRUITING

Sanmora Bespoke Clinical Research Solutions- Site Number : 8400043, East Orange

T5R 1W2

RECRUITING

Investigational Site Number : 1240007, Edmonton

M1B 3V4

RECRUITING

Investigational Site Number : 1240010, Scarborough Village

H1T 2M4

RECRUITING

Investigational Site Number : 1240006, Montreal

H3G 1A4

RECRUITING

Investigational Site Number : 1240003, Montreal

451-8511

RECRUITING

Investigational Site Number : 3920006, Nagoya

277-0871

RECRUITING

Investigational Site Number : 3920005, Kashiwa

802-0077

RECRUITING

Investigational Site Number : 3920008, Kitakyushu

004-0041

RECRUITING

Investigational Site Number : 3920002, Sapporo

065-0033

RECRUITING

Investigational Site Number : 3920001, Sapporo

247-0056

RECRUITING

Investigational Site Number : 3920011, Kamakura

411-0905

RECRUITING

Investigational Site Number : 3920010, Shimizu

113-8510

RECRUITING

Investigational Site Number : 3920004, Bunkyo

605-0981

RECRUITING

Investigational Site Number : 3920007, Kyoto

336-0963

RECRUITING

Investigational Site Number : 3920009, Saitama

01120

RECRUITING

Investigational Site Number : 4840004, Mexico City

00936

RECRUITING

University of Puerto Rico - Medical Sciences Campus- Site Number : 6300002, San Juan

0002

RECRUITING

Investigational Site Number : 7100004, Pretoria

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

Sanofi

INDUSTRY

NCT05731128 - A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab)) | Biotech Hunter | Biotech Hunter