Leronlimab in Combination With Regorafenib in Patients With CCR5+, Metastatic Colorectal Cancer

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

September 20, 2022

Primary Completion Date

May 27, 2023

Study Completion Date

August 10, 2023

Conditions
CCR5Microsatellite StableMetastaticColorectal Cancer
Interventions
DRUG

700mg leronlimab weekly dose

leronlimab is a humanized IgG4,κ monoclonal antibody (mAb) to the chemokine receptor CCR5

DRUG

80mg Regorafenib at week 1

Regorafenib is a small-molecule multiple kinase inhibitor

DRUG

120mg Regorafenib at week2

Regorafenib is a small-molecule multiple kinase inhibitor

DRUG

160 mg Regorafenib at week 3

Regorafenib is a small-molecule multiple kinase inhibitor

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Amarex Clinical Research

OTHER

lead

CytoDyn, Inc.

INDUSTRY