191
Participants
Start Date
March 9, 2023
Primary Completion Date
August 30, 2025
Study Completion Date
October 30, 2026
ICP-248
Eligible patients will receive ICP-248 orally as per the protocol, once daily for every 28 days as one treatment cycle (except for the food effect investigation phase), until progressive disease (PD), intolerable toxicity, withdrawal of consent, loss to follow-up, initiation of other anti-cancer therapy, death, or end of study, whichever occurs first.
ICP-248
Eligible patients will receive ICP-248 orally as specified in the treatment arm.
ICP-248+Orelabrutinib
Eligible patients will receive ICP-248 and Orelabrutinib as specified in the treatment arm.
ICP-248+Orelabrutinib
Eligible patients will receive ICP-248 and Orelabrutinib as specified in the treatment arm.
ICP-248 +Rituximab
Eligible patients will receive ICP-248 and Rituximab as specified in the treatment arm.
ICP-248+Orelabrutinib
Eligible patients will receive ICP-248 and Orelabrutinib as specified in the treatment arm.
ICP-248+Orelabrutinib+Rituximab
Eligible patients will receive ICP-248 and Orelabrutinib and Rituximab as specified in the treatment arm.
RECRUITING
Peking University Third Hospital, Beijing
RECRUITING
Shenyang Hospital Of China Medical University, Shenyang
RECRUITING
The Second Hospital of Dalian Medical University, Dalian
RECRUITING
Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai
RECRUITING
Jiangsu Province Hospital, Nanjing
RECRUITING
The First Affiliated Hospital of Anhui Medical University, Hefei
RECRUITING
The First Affiliated Hospital of Bengbu Medical College, Bengbu
RECRUITING
Shandong cancer hospital, Jinan
RECRUITING
The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou
RECRUITING
The First Affiliated Hospital of Nanchang University, Nanchang
RECRUITING
Jiangxi Cancer Hospital, Nanchang
RECRUITING
Fujian Medical University Union Hospital, Fuzhou
RECRUITING
The First Affiliated Hospital of Xiamen University, Xiamen
RECRUITING
The First Affiliated Hospital of Chongqing Medical University, Chongqing
RECRUITING
Hunan Cancer Hospital, Changsha
RECRUITING
The Central Hospital of Wuhan, Wuhan
RECRUITING
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan
RECRUITING
Henan Cancer Hospital, Zhengzhou
RECRUITING
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
RECRUITING
Sun Yat-Sen University Cancer Center, Guangzhou
RECRUITING
West China Hospital of Sichuan University, Chengdu
RECRUITING
Hematology Hospital, Chinese Academy of Medical Sciences, Tianjin
Beijing InnoCare Pharma Tech Co., Ltd.
INDUSTRY