50
Participants
Start Date
November 15, 2022
Primary Completion Date
August 31, 2026
Study Completion Date
August 31, 2026
nivolumab, docetaxel, cisplatin Group
Patients will be treated with nivolumab 360mg and plus docetaxel 60mg/m2 and cisplatin 60mg/m2 every 3 weeks for 3 cycles and will be evaluated for the operability. Patients with R0 resection will receive radiation 59.4 Gy in 27 fractions. Boost RT of 6.6 Gy in 3 fractions to tumor bed and/or gross tumor will be optional in patients who had R1-R2 resection. If tumors are regarded inoperable after neoadjuvant therapy (due to high risk of post-operative complication, or metastatic disease), they will be off from this study and receive the appropriate treatment, though they will be also included in the efficacy and safety analyses.
RECRUITING
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul
Myung-Ju Ahn
OTHER