Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages

PHASE4RecruitingINTERVENTIONAL
Enrollment

490

Participants

Timeline

Start Date

January 29, 2024

Primary Completion Date

July 29, 2026

Study Completion Date

July 29, 2027

Conditions
Recurrent MiscarriageRecurrent Pregnancy LossHabitual AbortionMiscarriageFertility Disorders
Interventions
DRUG

Prednisolone

Prednisolone tablets (20 mg daily for 6 weeks, 10 mg daily for 1 week, 5 mg daily for 1 week) or identical placebo tablets for 8 weeks

DRUG

Placebo

Placebo identical to prednisolone tablets

Trial Locations (1)

233ZA

RECRUITING

Leiden University Medical Center, Leiden

All Listed Sponsors
collaborator

Amsterdam University Medical Center

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Academisch Ziekenhuis Groningen

OTHER

collaborator

Maastricht University Medical Center

OTHER

collaborator

Isala

OTHER

collaborator

Catharina Ziekenhuis Eindhoven

OTHER

collaborator

Haaglanden Medical Centre

OTHER

collaborator

Amphia Hospital

OTHER

collaborator

Radboud University Medical Center

OTHER

collaborator

Jeroen Bosch Ziekenhuis

OTHER

collaborator

Onze Lieve Vrouwe Gasthuis

OTHER

lead

Leiden University Medical Center

OTHER