Domvanalimab and Zimberelimab in Advanced Liver Cancers

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

July 1, 2026

Study Completion Date

June 1, 2027

Conditions
Hepatobiliary CancerLiver CancerCholangiocarcinomaHepatocellular Carcinoma
Interventions
DRUG

Zimberelimab

Zimberelimab 360 mg IV every 3 weeks until disease progression, unacceptable toxicity, death, or discontinuation from the study treatment for any other reason.

DRUG

Domvanalimab

Domvanalimab 1200 mg IV every 3 weeks until disease progression, unacceptable toxicity, death, or discontinuation from the study treatment for any other reason.

Trial Locations (1)

75235

University of Texas Southwestern Medical Center, Dallas

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Arcus Biosciences, Inc.

INDUSTRY

collaborator

Cancer Prevention Research Institute of Texas

OTHER

lead

University of Texas Southwestern Medical Center

OTHER

NCT05724563 - Domvanalimab and Zimberelimab in Advanced Liver Cancers | Biotech Hunter | Biotech Hunter