E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

PHASE2RecruitingINTERVENTIONAL
Enrollment

302

Participants

Timeline

Start Date

August 8, 2024

Primary Completion Date

November 1, 2026

Study Completion Date

March 1, 2027

Conditions
Opioid Use DisorderCigarette Smoking
Interventions
BEHAVIORAL

Telehealth Motivational Counseling

At baseline, after randomization, participants will receive their first telehealth session (20\~25 minutes) from a counselor trained in motivational interviewing, harm reduction, and smoking cessation. Four additional sessions will be delivered (weeks 2, 3, 4, 6), 15\~20 minutes each.

DRUG

Nicotine Replacement Product

Combination nicotine replacement therapy with lozenges and patches. Participants are recommended to use the NRT according to product directions.

DEVICE

National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).

Participants are to use the electronic cigarette freely as replacement for smoking combustible cigarettes.

Trial Locations (2)

10016

RECRUITING

NYU Langone Health, New York

10461

NOT_YET_RECRUITING

Albert Einstein College of Medicine, The Bronx

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

NYU Langone Health

OTHER