750
Participants
Start Date
March 14, 2023
Primary Completion Date
March 23, 2026
Study Completion Date
March 23, 2026
Standard SBT
Weaning strategy in accordance with the care practices of the department, regarding the assessment of weaning criteria, SBT and extubation modalities.
SBT with T-piece or PSV
"\- Risk factors of WIPO~Step 1 : Daily assessment of weaning criteria in accordance with the study protocol.~Step 2 : Spontaneous breathing trial with T-piece for an hour. Measure of protein and haemoglobin by blood sample before and after the trial.~Step 3 : Reconnect the patient to the ventilator for at least 30 minutes and then extubate if SBT is successful.~If SBT failed : no extubation and new SBT the next day. Optimization of cardiac function or fluid overload will be in charge of the investigator.~\- No risk factors of WIPO~Step 1 : Daily assessment of weaning criteria in accordance with the study protocol.~Step 2 : Spontaneous breathing trial with pressure support ventilation (pressure support from 5 to 8 cmH20 - PEEP at 0 cmH20) for an hour.~Step 3 : Reconnect the patient to the ventilator for at least 30 minutes and then extubate if SBT is successful."
RECRUITING
CHU de Bordeaux, Bordeaux
RECRUITING
CHU de Clermont-Ferrand, Clermont-Ferrand
RECRUITING
CHU de Grenoble, Grenoble
RECRUITING
CHU de Lille, Lille
RECRUITING
CHU de Lyon - Hôpital Lyon Sud, Lyon
RECRUITING
CHU de Montpellier, Montpellier
RECRUITING
CHU de Nantes, Nantes
RECRUITING
CHU de Saint-Etienne, Saint-Etienne
RECRUITING
CHU de Toulouse, Toulouse
University Hospital, Clermont-Ferrand
OTHER