44
Participants
Start Date
March 21, 2023
Primary Completion Date
June 13, 2023
Study Completion Date
June 13, 2023
Clarithromycin
"Subjects receive the Clarithromycin intervention orally according to the following schedule:~Day 1: 1 Clarithromycin 500 mg immediate release (IR) tablet twice (Clarithromycin 500 mg BID).~Day 2: 2 Clarithromycin 500 mg immediate release (IR) tablets twice (Clarithromycin 1000 mg BID).~Day 3: 2 Clarithromycin 500 mg immediate release (IR) tablets once (Clarithromycin 1000 mg QD)."
Pimozide
"Subjects receive the Pimozide intervention orally according to the following schedule:~Days 1-3: Pimozide 6 mg immediate release (IR) once per day."
Placebo (Part 1)
Subjects receive matching placebo for treatments.
Moxifloxacin
Subjects receive Moxifloxacin 800 mg orally once on day 1.
Cobicistat
Subjects receive Cobicistat 450 mg orally once on day 1.
Moxifloxacin and Cobicistat
Subjects receive Moxifloxacin 800 mg and Cobicistat 450 mg orally once on day 1.
Placebo (Part 2)
Subjects receive matching placebo for treatments.
Spaulding Clinical Research, West Bend
Spaulding Clinical Research LLC
OTHER
Food and Drug Administration (FDA)
FED