Hiatal Hernia and Pulmonary Involvement

Active, not recruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

January 5, 2023

Primary Completion Date

March 31, 2024

Study Completion Date

December 31, 2025

Conditions
Hiatal HerniaInterstitial Lung Disease
Interventions
DIAGNOSTIC_TEST

Blood Collection

Prior to subject's surgical procedure, blood (about 3 tablespoons (44 mL)) will be collected through a needle in vein for research purposes. The UVA researchers will analyze the biomarkers that are expressed in subject's blood.

DIAGNOSTIC_TEST

Bronchoscopy

Following blood collection, the subject will undergo the bronchoscopy for research purposes. While in the operating room, a bronchoscope will be inserted through the breathing tube that is already been placed for the surgery. Subject's airways will be examined with the bronchoscope in both lungs. Ten tablespoons (150 mL) of saline solution will be injected into one of subject airways. The fluid will be re-collected by suctioning it back up with the bronchoscope. The fluid will be collected from the bronchscope.

Trial Locations (1)

22908

University of Virginia, Charlottesville

All Listed Sponsors
collaborator

American College of Chest Physicians

OTHER

lead

University of Virginia

OTHER