NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

March 8, 2023

Primary Completion Date

May 30, 2025

Study Completion Date

May 30, 2025

Conditions
Advanced CancerAdvanced Solid TumorNeoplasm MalignantMetastatic CancerMelanomaClassical Hodgkin LymphomaNon Small Cell Lung CancerRenal Cell CarcinomaUrothelial CarcinomaHead and Neck Squamous Cell CarcinomaSubungual Squamous Cell CarcinomaOesophageal CarcinomaMSI-H Colorectal CancerGastric CancerTriple Negative Breast CancerEndometrial CarcinomaPleural Mesothelioma
Interventions
DRUG

Fosifloxuridine Nafalbenamide

Intravenous infusion

DRUG

Leucovorin

Intravenous infusion

DRUG

Pembrolizumab

Intravenous infusion

DRUG

Docetaxel

Intravenous infusion

Trial Locations (4)

B15 2TH

Queen Elizabeth Hospital University Hospitals Birmingham NHS Foundation Trust, Birmingham

G12 0TN

The Beatson West of Scotland Cancer Centre, Glasgow

SE1 9RT

Guy's and St Thomas NHS Foundation Trust, London

M20 4BX

The Christie NHS Foundation Trust, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

NuCana plc

OTHER

NCT05714553 - NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours | Biotech Hunter | Biotech Hunter