Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)

PHASE2CompletedINTERVENTIONAL
Enrollment

94

Participants

Timeline

Start Date

February 6, 2023

Primary Completion Date

April 11, 2024

Study Completion Date

April 11, 2024

Conditions
Diabetic Macular Edema
Interventions
DRUG

Experimental: Group 1 - 50mg RZ402

RZ402 50 mg oral tablet, once daily for 3 months

DRUG

Experimental: Group 2 - 200mg RZ402

RZ402 200mg oral tablet, once daily for 3 months

DRUG

Experimental: Group 3 - 400mg RZ402

RZ402 400mg oral tablet, once daily for 3 months

OTHER

Placebo: Group 4 - Placebo

Placebo oral tablet, once daily for 3 months

Trial Locations (32)

30909

Rezolute Investigative Site, Augusta, Georgia, Augusta

32806

Rezolute Investigative Site, Orlando, FL, Orlando

33064

Rezolute Investigative Site, Deerfield Beach, Florida, Deerfield Beach

33308

Rezolute Investigative Site, Fort Lauderdale, Florida, Fort Lauderdale

66215

Rezolute Investigative Site, Lenexa, KS, Lenexa

77401

Rezolute Investigative Site, Bellaire, TX, Bellaire

78705

Rezolute Investigative Site, Austin, TX, Austin

93105

Rezolute Investigative Site, Santa Barbara, CA, Santa Barbara

93309

Rezolute Investigative Site, Bakersfield, CA, Bakersfield

85020-5505

Rezolute Investigative Site, Phoenix, Arizona, Phoenix

90211-1841

Rezolute Investigative Site, Beverly Hills, California, Beverly Hills

92835-3432

Rezolute Investigative Site, Fullerton, California, Fullerton

95356-9412

Rezolute Investigative Site, Modesto, California, Modesto

33067-3173

Rezolute Investigative Site, Coral Springs, Florida, Coral Springs

33880-3919

Rezolute Investigative Site, Winter Haven, Florida, Winter Haven

60452-2780

Rezolute Investigative Site, Oak Forest, Illinois, Oak Forest

62703-2403

Rezolute Investigative Site, Springfield, IL, Springfield

48073-6710

Rezolute Investigative Site, Royal Oak, MI, Royal Oak

55416-5538

Rezolute Investigative Site, Saint Louis Park, MN, Saint Louis Park

63128-1729

Rezolute Investigative Site, Saint Louis, Missouri, St Louis

89502-1605

Rezolute Investigative Site, Reno, Nevada, Reno

07003-3061

Rezolute Investigative Site, Bloomfield, NJ, Bloomfield

11021-5200

Rezolute Investigative Site, Great Neck, New York, Great Neck

10022-2793

Rezolute Investigative Site, New York, New York, New York

97477-1025

Rezolute Investigative Site, Springfield, Oregon, Springfield

29456-4118

Rezolute Investigative Site, Ladson, South Carolina, Ladson

78503-1518

Rezolute Investigative Site, McAllen, Texas, McAllen

75075-5025

Rezolute Investigative Site, Plano, Texas, Plano

78240-1502

Rezolute Investigative Site, San Antonio, TX, San Antonio

77384-4167

Rezolute Investigative Site, The Woodlands, TX, The Woodlands

76087-9133

Rezolute Investigative Site, Willow Park, Texas, Willow Park

24502-4271

Rezolute Investigative Site, Lynchburg, Virginia, Lynchburg

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Rezolute

OTHER

NCT05712720 - Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME) | Biotech Hunter | Biotech Hunter