A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

282

Participants

Timeline

Start Date

April 17, 2023

Primary Completion Date

April 30, 2028

Study Completion Date

April 30, 2028

Conditions
Primary Membranous Nephropathy
Interventions
DRUG

Zanubrutinib

Zanubrutinib capsules administered orally.

DRUG

Tacrolimus

Tacrolimus capsules administered orally.

Trial Locations (69)

1425

COMPLETED

Investigacion Clinica Aplicada, Ciudad Autonoma Buenos Aires

7600

COMPLETED

Centro de Investigaciones Medicas Mar Del Plata, Mar del Plata

10000

RECRUITING

Vseobecna Fakultni Nemocnice V Praze, Prague

14017

RECRUITING

The First Affiliated Hospital of Baotou Medical College, Baotou

27100

ACTIVE_NOT_RECRUITING

Istscientifico Di Pavia, Fondazione Smaugeri, Irccs, Clinica Del Lavoro E Della Riabilitazione, Pavia

38030

RECRUITING

Erciyes University Medical Faculty, Erciyes

40138

COMPLETED

Azienda Ospedaliera Universitaria Policlinico Santorsola Malpighi, Bologna

41380

RECRUITING

Kocaeli University Research and Application Hospital Department of Nephrology, Kocaeli

50000

RECRUITING

The First Hospital of Hebei Medical University, Shijiazhuang

60201

COMPLETED

Northshore University Healthsystem, Evanston

60611

COMPLETED

Northwestern University Feinberg School of Medicine, Chicago

77900

RECRUITING

Fakultni Nemocnice Olomouc, Olomouc

94304

ACTIVE_NOT_RECRUITING

Stanford University, Palo Alto

100029

RECRUITING

Beijing An Zhen Hospital, Capital Medical University, Beijing

100034

RECRUITING

Peking University First Hospital, Beijing

100044

COMPLETED

Peking University Peoples Hospital, Beijing

150001

RECRUITING

The Second Affiliated Hospital of Harbin Medical University, Harbin

200025

RECRUITING

Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai

200080

RECRUITING

Shanghai General Hospital, Shanghai

210029

RECRUITING

Jiangsu Province Hospital, Nanjing

214023

COMPLETED

Wuxi Peoples Hospital, Wuxi

236000

COMPLETED

Fuyang Peoples Hospital, Fuyang

250021

RECRUITING

Shandong Provincial Hospital, Jinan

261000

RECRUITING

Weifang Peoples Hospital, Weifang

266000

RECRUITING

The Affiliated Hospital of Qingdao University Branch South, Qingdao

272000

COMPLETED

Affiliated Hospital of Jining Medical University, Jining

310003

RECRUITING

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

310014

RECRUITING

Zhejiang Provincial Peoples Hospital, Hangzhou

315010

RECRUITING

The First Affiliated Hospital of Ningbo University, Ningbo

332000

COMPLETED

The First Affiliated Hospital of Nanchang University Branch Xianghu, Nanchang

350001

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

350005

RECRUITING

The First Affiliated Hospital of Fujian Medical University, Fuzhou

361003

RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

364029

ACTIVE_NOT_RECRUITING

Medical Company Llc, Grozny

410008

RECRUITING

Xiangya Hospital of Central South University, Changsha

430030

RECRUITING

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan

430060

RECRUITING

Renmin Hospital of Wuhan University, Wuhan

450052

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

471003

RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

473000

RECRUITING

Nanyang Central Hospital, Nanyang

510080

RECRUITING

Guangdong Provincial Peoples Hospital, Guangzhou

RECRUITING

The First Affiliated Hospital, Sun Yat Sen University, Guangzhou

518036

RECRUITING

Peking University Shenzhen Hospital, Shenzhen

530021

RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

545006

COMPLETED

Liuzhou Peoples Hospital, Liuzhou

550002

RECRUITING

Guizhou Provincial Peoples Hospital, Guiyang

610071

RECRUITING

Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital, Chengdu

643002

COMPLETED

Zigong First Peoples Hospital, Zigong Academy of Medical Sciences, Zigong

750004

RECRUITING

General Hospital of Ningxia Medical University, Yinchuan

830054

RECRUITING

The First Affiliated Hospital of Xinjiang Medical University, Ürümqi

91324-3528

ACTIVE_NOT_RECRUITING

Amicis Research Center, Northridge

55435-2130

ACTIVE_NOT_RECRUITING

Intermed Consultants, Minneapolis

89106-4852

ACTIVE_NOT_RECRUITING

Kidney Specialist of Southern Nevada (Ksosn), Las Vegas

45267-2827

COMPLETED

University of Cincinnati College of Medicine, Cincinnati

29306-3927

COMPLETED

Carolina Nephrology, Spartanburg

53226-1222

COMPLETED

Medical College of Wisconsin, Milwaukee

80420-011

ACTIVE_NOT_RECRUITING

Instituto Pro Renal Brasil, Curitiba

22270-060

COMPLETED

Ruschel Medicina E Pesquisa Clinica, Rio de Janeiro

04038-002

COMPLETED

Hospital Do Rim Fundacao Oswaldo Ramos, São Paulo

05403-000

ACTIVE_NOT_RECRUITING

Hcfmusp Hospital Das Clinicas Da Faculdade de Medicina Da Universidade de Sao Paulo, São Paulo

M1H 3G4

ACTIVE_NOT_RECRUITING

Ott Healthcare, Inc (Corporate Medical Centre), Scarborough

030012

COMPLETED

Shanxi Provincial Peoples Hospital, Taiyuan

92-213

COMPLETED

Spzoz Centralny Szpital Kliniczny Um W Lodzi, Lodz

10-561

COMPLETED

Wojewodzki Specjalistyczny Szpital W Olsztynie, Olsztyn

AB25 2ZN

ACTIVE_NOT_RECRUITING

Aberdeen Royal Infirmary, Aberdeen

SM5 1AA

COMPLETED

St Heliers Hospital, Carlshalton

DE22 3NE

ACTIVE_NOT_RECRUITING

Royal Derby Hospital, Derby

L9 7AL

COMPLETED

Aintree University Hospital, Liverpool

M13 9WL

COMPLETED

Manchester Royal Infirmary, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY

NCT05707377 - A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy | Biotech Hunter | Biotech Hunter