APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

February 28, 2023

Primary Completion Date

June 1, 2026

Study Completion Date

December 31, 2027

Conditions
NeuroblastomaSolid Tumor
Interventions
DRUG

APG-115

Orally once every other day(QOD) for 2 weeks and suspended for 1 week, 21 days as a cycle.

DRUG

APG-2575

Orally once a day (QD) for 21 days, 21 days as a cycle.

Trial Locations (3)

300060

RECRUITING

Tianjin Medical University Cancer Institute & Hospital, Tianjin

430030

RECRUITING

Tongji Hospital, Huazhong University of Science and Technology (HUST), Wuhan

Unknown

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

Sponsors
All Listed Sponsors
collaborator

Suzhou Yasheng Pharmaceutical Co., Ltd.

INDUSTRY

lead

Ascentage Pharma Group Inc.

INDUSTRY