NCT05698394View on ClinicalTrials.gov

Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

364

Participants

Timeline

Start Date

September 9, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

November 30, 2025

Conditions
Prenatal DepressionKetaminePostpartum Depression
Interventions
DRUG

Esketamine

0.2 mg/kg S-ketamine in 20 ml normal saline will be infused at a rate of 30 ml/h (infusion finished in 40 minutes) after giving birth

DRUG

Placebo

20 ml normal saline will be infused at a rate of 30 ml/h (infusion finished in 40 minutes) after giving birth.

Trial Locations (4)

100034

Peking University First Hospital, Beijing

Unknown

Hunan Provincial Maternal and Child Health Care Hospital, Changsha

Women's Hospital of Nanjing Medical University, Nanjing

Women's Hospital, Zhejiang University School of Medicine, Hangzhou

All Listed Sponsors
lead

Peking University First Hospital

OTHER

NCT05698394 - Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth | Biotech Hunter | Biotech Hunter