200
Participants
Start Date
September 13, 2022
Primary Completion Date
December 30, 2022
Study Completion Date
May 31, 2023
Corfluvec component 1 low dose
Participants will receive single intranasal injection of H3N2 recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2
Corfluvec component 2 low dose
Participants will receive single intranasal injection of H1N1pdm09 recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2
Corfluvec component 1 high dose
Participants will receive single intranasal injection of H3N2 recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2
Corfluvec component 2 high dose
Participants will receive single intranasal injection of H1N1pdm09 recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2
Corfluvec low dose
Participants will receive two intranasal injections of recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2 tree weeks apart (H3N2 →H1N1pdm09)
Corfluvec high dose
Participants will receive two intranasal injections of recombinant attenuated influenza vector with modified NS gene coding for the N protein fragment of SARS-CoV-2 tree weeks apart (H3N2 →H1N1pdm09)
Placebo
Participants will receive two intranasal injections of placebo three weeks apart
Pavlov First State Medical University of St. Petersburg, Saint Petersburg
Smorodintsev Research Institute of Influenza, Saint Petersburg
MDP-CRO, LLC
UNKNOWN
St. Petersburg State Pavlov Medical University
OTHER
Tatyana Zubkova
OTHER