Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

December 1, 2025

Study Completion Date

December 1, 2025

Conditions
Asthma in ChildrenNonadherence, Medication
Interventions
DRUG

Maintenance ICS and Symptom Driven SABA

In this intervention, patients will be assigned to a standard therapy with a maintenance inhaled corticosteroid (Flovent) and an as needed short-acting beta-agonist and their adherence to this regimen will be assessed and compared to patients taking a regimen with an as needed inhaled corticosteroid and long-acting beta-agonist.

DRUG

Symptom-driven budesonide/formoterol combination

In this intervention, patients will be assigned to a symptom-driven budesonide/formoterol combination therapy (Symbicort) and their adherence to this regimen will be assessed and compared to patients taking a standard therapy with a maintenance inhaled corticosteroid and as needed short-acting beta-agonist.

Trial Locations (1)

63110

Washington University in St. Louis School of Medicine, St Louis

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

Washington University School of Medicine

OTHER