Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Systemic Lupus Erythematosus

PHASE2RecruitingINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

April 29, 2023

Primary Completion Date

August 25, 2025

Study Completion Date

May 30, 2026

Conditions
Systemic Lupus Erythematosus, SLE
Interventions
DRUG

Orelabrutinib (Low Dose)

Subjects will be administered with lower dose of Orelabrutinib orally once daily in combination with SOC therapy

DRUG

Orelabrutinib (High Dose)

Subjects will be administered with higher dose of Orelabrutinib orally once daily in combination with SOC therapy

DRUG

Orelabrutinib Placebo

Subjects will be administered with Orelabrutinib Placebo orally once daily in combination with SOC therapy

Trial Locations (41)

100000

RECRUITING

Peking University People's Hospital, Beijing

100029

NOT_YET_RECRUITING

China-Japan Friendship Hospital, Beijing

100050

RECRUITING

Beijing Friendship Hospital, Capital Medical University, Beijing

110004

RECRUITING

Shengjing Hospital of china medical university, Shenyang

130021

RECRUITING

Jilin Provincial People's Hospital, Changchun

161005

RECRUITING

The first hospital of Qiqihar, Qiqihar

200000

RECRUITING

Changhai Hospital of Shanghai, Shanghai

RECRUITING

Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

215004

RECRUITING

The Second Affiliated Hospital of Soochow University, Suzhou

221000

RECRUITING

Xuzhou Central Hospital, Xuzhou

230022

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

233099

RECRUITING

The first affiliated hospital of bengbu medical college, Bengbu

256699

RECRUITING

Affiliated Hospital of Binzhou Medical College, Binzhou

272002

RECRUITING

Jining First People's Hospital, Jining

276034

RECRUITING

Linyi People's Hospital, Linyi

300000

NOT_YET_RECRUITING

Tianjin Medical University General Hospital, Tianjin

313002

RECRUITING

The Third People's Hospital of Huzhou, Huzhou

315010

RECRUITING

The First Hospital of Ningbo, Ningbo

317500

RECRUITING

The First People's Hospital of Wenling, Wenling

325099

RECRUITING

Wenzhou People's Hospital, Wenzhou

330006

RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

332000

RECRUITING

Jiujiang NO.1 People's Hospital, Jiujiang

361009

RECRUITING

The First Affiliated Hospital of XiaMen University, Xiamen

410000

NOT_YET_RECRUITING

The Second XIANGYA Hospital Of Central South University, Changsha

412000

RECRUITING

Zhuzhou Central Hospital, Zhuzhou

413000

RECRUITING

Yiyang Central Hospital, Yiyang

430022

RECRUITING

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan

450052

RECRUITING

First Affiliated Hospital of Zhengzhou University, Zhengzhou

471003

RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

510080

RECRUITING

The First Affiliated Hospital,Sun Yat-sen University, Guangzhou

515041

RECRUITING

The first affiliated hospital of shantou university medical college, Shantou

518107

RECRUITING

The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen

541001

RECRUITING

Affiliated Hospital of Guilin Medical University, Guilin

710061

RECRUITING

The First Affiliated Hospital of Xi 'an Jiaotong University, Xi’an

830000

RECRUITING

Xinjiang Uygur Autonomous Region People's Hospital, Ürümqi

071030

RECRUITING

Affiliated Hospital of HeBei University, Baoding

050051

RECRUITING

Hebei People's Hospital, Shijiazhuang

Contact: Junsong Li

RECRUITING

Daqing Oilfield General Hospital, Daqing

010000

NOT_YET_RECRUITING

Affiliated Hospital of Inner Mongolia Medical University, Hohhot

030001

RECRUITING

The First Hospital of Shanxi Medical University, Taiyuan

RECRUITING

The Second Hospital of Shanxi Medical University, Taiyuan

All Listed Sponsors
lead

Beijing InnoCare Pharma Tech Co., Ltd.

INDUSTRY